"Clinical Pharmacology of Carbapenems in Infants and Children"
نویسندگان
چکیده
منابع مشابه
Clinical Pharmacology of Cefepime in Infants and Children
Cefepime is a fourth-generation cephalosporin which is approved in Europe and in the USA. Food and Drug Administration (FDA) approves cefepime in the treatment of febrile neutropenia. Cefepime is active against gram-negative microorganisms such as Escherichia coli, Haemophilus influenzae, Enterobacter, Klebsiella, Morganella, Neisseria, Serratia, and Proteus species. Cefepime is also active aga...
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The pharmacokinetics of cefadroxil suspension were studied in 30 children, 13 months to 12 years of age (mean age, 5.7 years). Average peak concentrations in serum of 11 to 14 mug/ml and of 7 to 10 mug/ml after 15- and 10-mg/kg doses, respectively, were not substantially affected by the feeding status. The serum half-life values were 1.3 to 1.5 h. Cefadroxil was detected in saliva of all childr...
متن کاملClinical Pharmacology of Ampicillin in Neonates and Infants: Effects and Pharmacokinetics
Ampicillin is a bactericidal antibiotic, it penetrates into the bacterial wall better than penicillin G and is active against gram-negative bacteria that are resistant to penicillin G. Ampicillin has a broad-spectrum antimicrobial activity and is the most widely used antibiotic for treating infections caused by Listeria, β-lactamase-negative Haemophilus, enterococci, Shigella, streptococci, Esc...
متن کاملClinical Pharmacology of Ceftriaxone in Neonates and Infants: Effects and Pharmacokinetics
Ceftriaxone is a versatile and useful "third-generation" cephalosporin that needs to be administered once-daily. Ceftriaxone is a β-lactamase-resistant cephalosporin. It is active against important gram-positive and most gram-negative bacteria. The MIC90s of ceftriaxone are 0.1 µg/ml for Escherichia coli, 0.1 µg/ml for Klebsiella species, 0.2 µg/ml for Proteus species, 0.3 µg/ml for Enterobacte...
متن کاملClinical Pharmacology of Cefotaxime in Neonates and Infants: Effects and Pharmacokinetics
Cefotaxime is a bactericidal "third generation" cephalosporin has a broad-spectrum activity against gram-positive microorganisms and exceptional activity against most gram-negative microorganisms. Cefotaxime is widely considered to be the antibiotic of choice for the management of neonatal meningitis and sepsis caused by gram-negative bacteria. Cefotaxime is active against Neisseria meningitis,...
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ژورنال
عنوان ژورنال: Biomedical Journal of Scientific and Technical Research
سال: 2022
ISSN: ['2574-1241']
DOI: https://doi.org/10.26717/bjstr.2022.46.007305